The number of grapes that are used to make a bottle of wine can vary significantly depending on the size of the grapes and the yield of the wine.
As a rough estimate, it takes about 2.5 to 3 pounds of grapes to make a bottle of wine. This translates to approximately 600 to 720 grapes per bottle, depending on the size of the grapes.
However, it is important to note that this is just a rough estimate, and the actual number of grapes used to make a bottle of wine can vary significantly depending on the specific type of grapes and the wine making process. Some wines may be made from a blend of different types of grapes, and the yield of the wine can be affected by a number of factors, such as the grape variety, the climate, and the winemaking techniques.